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| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Peep |
| 2. | Perekonnanimi | Veski |
| 3. | Töökoht | Tartu Ülikooli Farmaatsia instituut |
| 4. | Ametikoht | Ravimite tehnoloogia ja biofarmaatsia professor, instituudi juhataja |
| 5. | Sünniaeg | 10.01.1950 (päev.kuu.aasta) |
| 6. | Haridus | Semmelweisi Ülikool (Budapest) - lõpetanud 1975.aastal, proviisor |
| 7. | Teenistuskäik | 1980-1981 - TÜ farmaatsia instituudi assistent 1981-1986 - TÜ farmaatsia instituudi vanemõpetaja 1986-1998 - TÜ farmaatsia instituudi dotsent 1998 - - TÜ farmatseutilise tehnoloogia ja biofarmaatsia professor, farmaatsia instituudi juhataja |
| 8. | Teaduskraad | Bioloogiateaduste kandidaat Farmaatsiadoktor |
| 9. | Teaduskraadi välja andnud asutus, aasta |
Ungari Teaduste Akadeemia, 1980 Helsingi Ülikool, 1994 |
| 10. | Tunnustused | Hispaania Kuningliku Farmaatsia-akadeemia korrespondentliige, 2003 |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
Euroopa Farmakopöa Ekspertkomisjoni G12 (Galenical Products) liige TÜ Arstiteaduskonna prodekaan 01.02.1998-15.03.2002 EAFP (European Association of faculties of Pharmacy) juhatuse liige EUFEPS (European Federation for Pharmaceutical Sciences) mitme töögrupi liige EMEA ekspert EV Sotsiaalministeeriumi juures asuva farmaatsiaterminoloogia komisjoni liige Ajakirja European Journal of Pharmaceutical Sciences retsensent Ajakirjade "Ars Pharmaceutica" ja Euro Pharma Faculties News" toimetuskolleegiumi liige |
| 12. | Juhendamisel kaitstud väitekirjad |
Eve-Irene Lepist, DSc, 2000, juh. Peep Veski. Oral peptide prodrugs - studies on stability and absorption. Tartu Ülikool Ivika Leik, MSc, 1996, juh. Peep Veski. Ravimi toimekestvuse reguleerimine kõvades zhelatiinkapslites ex tempore moodustuva kaltsiumalginaadi abil. Tartu Ülikool Piret Ansko, MSc, 1996, juh. Peep Veski. Raviaine vabanemise kiirus ja kineetika kui peroraalsete tahkete ravimpreparaatide toime kestvust reguleerivad tegurid. Tartu Ülikool Eve-Irene Lepist, MSc, 1995, juh. Peep Veski. Naatriunalginaadi geelistumise mehhanism ja pressimisjõu toime raviaine vabanemisele kõvadest zhelatiinkapslitest. Tartu Ülikool |
| 13. | Teadustöö põhisuunad | Raviainet modifitseeritult vabastavate (mudel)preparaatide väljatöötamine - ajaliselt reguleeritud vabanemisega (time-controlled release) preparaatide koostise ja valmistamise tehnoloogia väljatöötamine, nimetatud preparaatide biofarmatseutilise kvaliteedi hindamine, preparaatide kronobiofarmatseutilised uuringud - jämesooles/käärsooles raviainet vabastavate (colon-specific) peroraalselt manustatavate tahkete ravimvormide väljatöötamine ja nende biofarmatseutilise kvaliteedi hindamine - erinevate biopolümeeride (alginaadid, kitosaan) kasutamine raviaine vabanemist reguleeriva abiainena Peroraalselt manustatavate tahkete ravimpreparaatide in vitro-in vivo korrelatsiooni uurimine Raviainet modifitseeritult vabastavate peroraalsete tahkete ravimpreparaatide in vitro uurimismeetodite täiustamine Peroraalselt manustatavate tahkete ravimpreparaatide (eelkõige kõvakapslite) koostise väljatöötamine ja täiustamine, nende preparaatide biofarmatseutiline hindamine |
| 14. | Jooksvad grandid | |
| 15. | Teaduspublikatsioonid |
Nykänen, P., Sten, T., Jürjenson, H., Veski, P., Marvola, M., 2003. citric acid as a pH-regulating additive in granules and the tablet matrix in enteric-coated formulations for colon-specific drug delivery. Pharmazie, 59. 268-273. Säkkinen, M., Linna, A., Ojala, S., Jürjenson, H., Veski, P., Marvola, M., 2003. In vivo evaluation of matrix granules containing microcrystalline chitosan as a gel-forming excipient. International Journal of Pharmaceutics, 250, 227-237. Säkkinen, M., Tuononen, T., Jürjenson, H. Veski, P. Marvola, M., 2003.Evaluation of microcrystalline chitosan for gastro-retentive drug delivery. European Journal of Pharmaceutical Sciences, 19, 345-353. Raal, A., Hinrikus, T., Veski, P., 2002.The teaching of pharmacy at the University of Tartu through the centuries. Pharmacy Education, 2(2), 93-96 Halsas, M., Penttinen, T., Veski, P., Jürjenson, H., Marvola, M., 2001. Time- controlled release pseudoephedrine tablets: bioavailability and in vitro/in vivo correlations. Die Pharmazie, 56, 9, 718-723. Nykänen, P., Lempää, S., Aaltonen, M.-L., Jürjenson, H., Veski, P., Marvola, M., 2001. Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon. International Journal of Pharmaceutics, 229, 1-2, 155-162. Lepist, E.-I., Kusk, T., Larsen, D.H., Andersen, D., Frokjaer, S., Taub, M.E., Veski, P., Lennernäs, H., Friedrichsen, G., Steffansen, B., 2000. Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter. European Journal of Pharmaceutical Sciences, 11, 1, 43-50. Säkkinen, M., Seppälä, U., Heinänen, P., Veski, P., Marvola, M., 2000. in vitro evaluation of microcrystalline chitosan and its characteristics as a release rate modifying excipient. Proc. 3rd World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 41-42. Ansko, P., Paavo, M., Veski, P., 1999. Using of the different increasing pH methods for dissolution test of nifedipine modified release formulations. European Journal of Pharmaceutical Sciences, 8S 39. Halsas, M., Hietala, Veski, P., Jürjenson, H., Marvola, M., 1999. Morning versus evening dosing of ibuprofen using conventional and time-controlled release formulations. International Journal of Pharmaceutics, 189, 1, 179-185. Nykänen, P. Krogars, M., Säkkinen, M., Heinämäki, J., Jürjenson, H., Veski, P., Marvola, M., 1999. Organic acids as excipients in matrix granules for colon-specific drug delivery. International Journal of Pharmaceutics, 184, 3, 251-261. Halsas, M., Ervasti, P., Veski, P., Jürjenson, H, Marvola, M., 1998. Biopharmaceutical evaluation of time-controlled press-coated tablets containing polymers to adjust drug release. European Journal of Drug Metabolism and Pharmacokinetics, 23, 2, 190-196. Halsas, M., Simelius, R., Kiviniemi, A., Veski, P., Jürjenson, H., Marvola, M., 1998. Effect of different combinations of HPMC on bioavailability of ibuprofen from press-coated time-controlled tablets. S.T.P. Pharma, 8, 3, 155-161. Petri, G., Veszki, P., Oroszlan, P., Turiak, Gy., 1996. Cannabinoid content of foreign and domestic fibre hemp cultivated in Hungary. Acta Agronomica Hungarica, 44, 2, 133-140. Petri, G., Nyiredy, Sz., Veszki, P., Oroszlan, P., Turiak, Gy., 1995. Gas-chromatographic analyses of cannabinoids on tandem columns. Acta Pharm. Hung., 65, 63-67. Veski, P., Lepist, I., Jürjenson, H., Marvola, M., 1995. Prolongation of drug absorption from hard gelatin capsules using different viscosity grades of sodium alginates as diluents. Proc. 1st World Meeting APGI/APV, 929-930. Sirkiä, T., Salonen, H., Veski, P., Jürjenson, H., Marvola, M., 1994. Biopharmaceutical evaluation of new prolonged-release press-coated ibuprofen tablets containing sodium alginate to adjust drug release. Int. J. Pharm., 107, 179-187. Veski, P., Marvola, M., Smal, J., Heiskanen, I., Jürjenson, H., 1994. Biopharmaceutical evaluation of pseudoephedrine hydrochloride capsules containing different grades of sodium alginate. Int. J. Pharm., 111, 171-179. Veski, P., Marvola, M., 1993. Sodium alginates as diluents in hard gelatin capsules containing ibuprofen as a model drug. Pharmazie, 48, 757-760. Veski, P., Marvola, M., Klinge, E., Jürjenson, H., 1993. Bioavailability of ibuprofen from hard gelatin capsules containing sodium alginates Eur. J. Drug Metab. Pharmacokinet., Special Issue IV, 158-163. Veski, P., Marvola, M., 1991. Design and use of equipment for simulation of plug formation in hard gelatin capsule filling machines. Acta Pharm. Fenn., 100, 19-25. VerzarPetri G., Veski P., Meszaros S. Morphological comparison of local hemp varieties Acta Agronomica Hungarica 30 (3-4): 350-371 1981. Veszki, P., Verzar-Petri, G., Mezaros, S., 1980. Comparative phytochemical study on cannabinoid composition of the geographical varieties of the Cannabis sativa L. under the same conditions. Acta Horticulturae, 96, 95-103. Lemberkovics E., Veszki P., VerzarPetri G. Trka A. Contributions to the essential oil composition of the flowers and leaves of Cannabis sativa L. Planta Medica 36(3): 271-272 1979. VerzarPetri G., Veszki P., Meszaros S.. Comparative phytochamical study of the cannabinoid composition of geographical varieties of Cannabis sativa L. under the same conditions. Planta Medica 36(3): 258-259 1979. |
viimati muudetud: 09.10.2005
| Curriculum Vitae (CV) | ||
| 1. | First Name | Peep |
| 2. | Surname | Veski |
| 3. | Institution | Institute of Pharmacy, University of Tartu |
| 4. | Position | Professor of Pharmaceutical Technology and Biopharmaceutics, Head of the Institute |
| 5. | Date of birth | 10.01.1950 (day.month.year) |
| 6. | Education | Semmelweis University - graduated in 1975, pharmacist |
| 7. | Research and professional experience |
1980-1981 - Assistant Professor, Institute of Pharmacy, University of Tartu 1981-1986 - Senior Lecturer, Institute of Pharmacy, University of Tartu 1986-1998 - Associate Professor, Institute of Pharmacy, University of Tartu 1998- - Professor of Pharmaceutical Technology and Biopharmaceutics, head of the Institute of Pharmacy, University of Tartu |
| 8. | Academic degree | Candidate of Biological Sciences |
| 9. | Dates and sites of earning the degrees |
Hungarian Academy of Sciences, 1980 University of Helsinki, 1994 |
| 10. | Honours/awards | Correspondant Academicien of the Spanish Royal Academy of Pharmacy, 2003 |
| 11. | Research-administrative experience |
Member of Group of Experts 12 (Galenical Products) - European Pharmacopoeia Vice-Dean of the Faculty of Medicine - 01.02.1998-15.03.2002 Member of the Executive Committee of European Association of Faculties of Pharmacy Member of several working group of European Federation for Pharmaceutical Sciences Expert of EMEA Member of the Commission of Pharmaceutical Terminology of the Ministry of Social Affairs, Estonia Reviewer of European Journal of Pharmaceutical Sciences Member of the Editorial Board of the "Ars Pharmaceutica" and "Euro Pharma Faculties News" |
| 12. | Supervised dissertations |
Eve-Irene Lepist, DSc, 2000, superv. Peep Veski. Oral peptide prodrugs - studies on stability and absorption. Tartu Ülikool Ivika Leik, MSc, 1996, superv. Peep Veski. Ravimi toimekestvuse reguleerimine kõvades zhelatiinkapslites ex tempore moodustuva kaltsiumalginaadi abil. Tartu Ülikool Piret Ansko, MSc, 1996, superv. Peep Veski. Raviaine vabanemise kiirus ja kineetika kui peroraalsete tahkete ravimpreparaatide toime kestvust reguleerivad tegurid. Tartu Ülikool Eve-Irene Lepist, MSc, 1995, superv. Peep Veski. Naatriunalginaadi geelistumise mehhanism ja pressimisjõu toime raviaine vabanemisele kõvadest zhelatiinkapslitest. Tartu Ülikool |
| 13. | Current research program | Evaluation of modified-release (model)formulations - time-controlled-release formulations - biopharmaceutical quality of those formulations - chronobiopharmaceutical investigations - evaluation of colon-specific drug delivery systems and biopharmaceutical quality of those DDS - using different biopolymers (alginates, chitosan) as drug release regulating excipients In vitro-in vivo correlations of biopharmaceutical characteristics of oral solid dosage forms Improvement of in vitro methods for dissolution test of modified-release solid oral dosage forms Evaluation and improvement of the composition of oral solid dosage forms (hard capsules), biopharmaceutical quality of those formulations |
| 14. | Current grant funding | |
| 15. | List of most important publications |
Nykänen, P., Sten, T., Jürjenson, H., Veski, P., Marvola, M., 2003. citric acid as a pH-regulating additive in granules and the tablet matrix in enteric-coated formulations for colon-specific drug delivery. Pharmazie, 59. 268-273. Säkkinen, M., Linna, A., Ojala, S., Jürjenson, H., Veski, P., Marvola, M., 2003. In vivo evaluation of matrix granules containing microcrystalline chitosan as a gel-forming excipient. International Journal of Pharmaceutics, 250, 227-237. Säkkinen, M., Tuononen, T., Jürjenson, H. Veski, P. Marvola, M., 2003.Evaluation of microcrystalline chitosan for gastro-retentive drug delivery. European Journal of Pharmaceutical Sciences, 19, 345-353. Raal, A., Hinrikus, T., Veski, P., 2002.The teaching of pharmacy at the University of Tartu through the centuries. Pharmacy Education, 2(2), 93-96 Halsas, M., Penttinen, T., Veski, P., Jürjenson, H., Marvola, M., 2001. Time- controlled release pseudoephedrine tablets: bioavailability and in vitro/in vivo correlations. Die Pharmazie, 56, 9, 718-723. Nykänen, P., Lempää, S., Aaltonen, M.-L., Jürjenson, H., Veski, P., Marvola, M., 2001. Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon. International Journal of Pharmaceutics, 229, 1-2, 155-162. Lepist, E.-I., Kusk, T., Larsen, D.H., Andersen, D., Frokjaer, S., Taub, M.E., Veski, P., Lennernäs, H., Friedrichsen, G., Steffansen, B., 2000. Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter. European Journal of Pharmaceutical Sciences, 11, 1, 43-50. Säkkinen, M., Seppälä, U., Heinänen, P., Veski, P., Marvola, M., 2000. in vitro evaluation of microcrystalline chitosan and its characteristics as a release rate modifying excipient. Proc. 3rd World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 41-42. Ansko, P., Paavo, M., Veski, P., 1999. Using of the different increasing pH methods for dissolution test of nifedipine modified release formulations. European Journal of Pharmaceutical Sciences, 8S 39. Halsas, M., Hietala, Veski, P., Jürjenson, H., Marvola, M., 1999. Morning versus evening dosing of ibuprofen using conventional and time-controlled release formulations. International Journal of Pharmaceutics, 189, 1, 179-185. Nykänen, P. Krogars, M., Säkkinen, M., Heinämäki, J., Jürjenson, H., Veski, P., Marvola, M., 1999. Organic acids as excipients in matrix granules for colon-specific drug delivery. International Journal of Pharmaceutics, 184, 3, 251-261. Halsas, M., Ervasti, P., Veski, P., Jürjenson, H, Marvola, M., 1998. Biopharmaceutical evaluation of time-controlled press-coated tablets containing polymers to adjust drug release. European Journal of Drug Metabolism and Pharmacokinetics, 23, 2, 190-196. Halsas, M., Simelius, R., Kiviniemi, A., Veski, P., Jürjenson, H., Marvola, M., 1998. Effect of different combinations of HPMC on bioavailability of ibuprofen from press-coated time-controlled tablets. S.T.P. Pharma, 8, 3, 155-161. Petri, G., Veszki, P., Oroszlan, P., Turiak, Gy., 1996. Cannabinoid content of foreign and domestic fibre hemp cultivated in Hungary. Acta Agronomica Hungarica, 44, 2, 133-140. Petri, G., Nyiredy, Sz., Veszki, P., Oroszlan, P., Turiak, Gy., 1995. Gas-chromatographic analyses of cannabinoids on tandem columns. Acta Pharm. Hung., 65, 63-67. Veski, P., Lepist, I., Jürjenson, H., Marvola, M., 1995. Prolongation of drug absorption from hard gelatin capsules using different viscosity grades of sodium alginates as diluents. Proc. 1st World Meeting APGI/APV, 929-930. Sirkiä, T., Salonen, H., Veski, P., Jürjenson, H., Marvola, M., 1994. Biopharmaceutical evaluation of new prolonged-release press-coated ibuprofen tablets containing sodium alginate to adjust drug release. Int. J. Pharm., 107, 179-187. Veski, P., Marvola, M., Smal, J., Heiskanen, I., Jürjenson, H., 1994. Biopharmaceutical evaluation of pseudoephedrine hydrochloride capsules containing different grades of sodium alginate. Int. J. Pharm., 111, 171-179. Veski, P., Marvola, M., 1993. Sodium alginates as diluents in hard gelatin capsules containing ibuprofen as a model drug. Pharmazie, 48, 757-760. Veski, P., Marvola, M., Klinge, E., Jürjenson, H., 1993. Bioavailability of ibuprofen from hard gelatin capsules containing sodium alginates Eur. J. Drug Metab. Pharmacokinet., Special Issue IV, 158-163. Veski, P., Marvola, M., 1991. Design and use of equipment for simulation of plug formation in hard gelatin capsule filling machines. Acta Pharm. Fenn., 100, 19-25. VerzarPetri G., Veski P., Meszaros S. Morphological comparison of local hemp varieties Acta Agronomica Hungarica 30 (3-4): 350-371 1981. Veszki, P., Verzar-Petri, G., Mezaros, S., 1980. Comparative phytochemical study on cannabinoid composition of the geographical varieties of the Cannabis sativa L. under the same conditions. Acta Horticulturae, 96, 95-103. Lemberkovics E., Veszki P., VerzarPetri G. Trka A. Contributions to the essential oil composition of the flowers and leaves of Cannabis sativa L. Planta Medica 36(3): 271-272 1979. VerzarPetri G., Veszki P., Meszaros S.. Comparative phytochamical study of the cannabinoid composition of geographical varieties of Cannabis sativa L. under the same conditions. Planta Medica 36(3): 258-259 1979. |
last updated: 09.10.2005
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